Identification of the salusin-β receptor using proteoliposomes embedded with endogenous membrane proteins
نویسندگان
چکیده
منابع مشابه
Salusin-β as a powerful endogenous antidipsogenic neuropeptide.
Salusin-β is an endogenous parasympathomimetic peptide, predominantly localized to the hypothalamus and posterior pituitary. Subcutaneously administered salusin-β (50 nmol/mouse) significantly increased water intake but did not affect locomotor activity or food intake. The salusin-β-induced increase in water intake was completely abrogated by pretreatment with muscarinic antagonist, atropine su...
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Background:Brucella spp. are facultative intracellular pathogens that can cause chronic infections in many tissues and organs. Objectives: To investigate serum dermcidin, salusin-alpha, salusin-beta and TNF-alpha levels and their correlation with each other in patients with acute brucellosis. Methods: From 50 patients hospitalized upon...
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Reconstitution of membrane proteins into lipid bilayers is a powerful tool to analyze functional as well as structural areas of membrane protein research. First, the proper incorporation of a purified membrane protein into closed lipid vesicles, to produce proteoliposomes, allows the investigation of transport and/or catalytic properties of any membrane protein without interference by other mem...
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data envelopment analysis (dea) is a powerful tool for measuring relative efficiency of organizational units referred to as decision making units (dmus). in most cases dmus have network structures with internal linking activities. traditional dea models, however, consider dmus as black boxes with no regard to their linking activities and therefore do not provide decision makers with the reasons...
Discrimination of β-Barrel Membrane Proteins Using Machine Learning Techniques
β-barrel membrane proteins (TMBs) perform a variety of functions in living organisms and these proteins contain β-strands as their membrane spanning segments. The membrane spanning segments of TMBs contain several charged and polar residues in contrast with a stretch of hydrophobic amino acid residues in transmembrane helical (TMH) proteins. Hence, most predictive schemes, which are successful ...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2018
ISSN: 2045-2322
DOI: 10.1038/s41598-018-35740-6